NCT04686058

Sedation Techniques for Outpatient Colonoscopy

Propofol Patient-controlled Sedation Versus Target-controlled Infusion in Outpatient Colonoscopy

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 105 (actual)
• Sponsor: Universiti Kebangsaan Malaysia Medical Centre · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

This was a prospective, randomized, single-blind controlled clinical trial comparing three sedative regimens for outpatient colonoscopy.

Detailed description

This was a prospective, randomized, single-blind controlled clinical trial comparing target-controlled infusion (TCI) with propofol and patient-controlled sedation (PCS) with propofol, to conventional combination of midazolam and pethidine, in terms of quality and safety of sedation, and patient recovery during outpatient colonoscopy.

Conditions

• Colonoscopy

Interventions

Type	Name	Description
DRUG	Propofol 10 MG/ML Injection
DRUG	Midazolam injection
DRUG	Pethidine Hydrochloride 50 Mg/mL Solution for Injection
DEVICE	target controlled infusion pump
DEVICE	patient-controlled sedation pump

Timeline

• Start date: 2014-03-01
• Primary completion: 2014-12-01
• Completion: 2014-12-01
• First posted: 2020-12-28
• Last updated: 2020-12-28

Locations

1 site across 1 country: Malaysia