Clinical Trials Directory

Trials / Terminated

TerminatedNCT04684914

HepTcell Immunotherapy in Patients With Inactive Chronic Hepatitis B (CHB)

Phase 2, Double-blind, Randomized, Placebo-controlled Study of HepTcell (Adjuvanted FP-02.2) as an Immunotherapeutic Vaccine in Treatment-naïve Patients With Inactive Chronic Hepatitis B (CHB)

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
87 (actual)
Sponsor
Altimmune, Inc. · Industry
Sex
All
Age
18 Years – 65 Years
Healthy volunteers
Not accepted

Summary

A study to evaluate the antiviral effects, immunogenicity, and safety of HepTcell in treatment-naive patients with inactive chronic hepatitis B (CHB) and low hepatitis B surface antigen (HBsAg) levels.

Conditions

Interventions

TypeNameDescription
BIOLOGICALHepTcellIntramuscular injection
DRUGPlaceboIntramuscular injection

Timeline

Start date
2020-12-26
Primary completion
2024-03-27
Completion
2024-04-17
First posted
2020-12-28
Last updated
2025-12-08
Results posted
2025-12-08

Locations

21 sites across 5 countries: United States, Canada, Germany, Spain, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT04684914. Inclusion in this directory is not an endorsement.