NCT04683757

The Establishment of a Survival Prediction Model for ER Positive / HER-2 Negative Advanced Breast Cancer

A Prospective Cohort Study： the Establishment of a Survival Prediction Model for ER Positive / HER-2 Negative Advanced Breast Cancer

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 288 (estimated)
• Sponsor: Ying Wang · Academic / Other
• Sex: Female
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

This project is a prospective, clinical cohort study initiated by researchers to study the high-risk factors affecting the overall survival of newly diagnosed ER + / HER2 - advanced breast cancer patients and to establish a prediction model of ER + / HER2 - advanced breast cancer patients affecting overall survival. This project is the first prospective prediction model for the survival of patients with advanced breast cancer, and it is also the first time to establish a survival prediction model for ER-positive / HER2 negative advanced breast cancer suitable for China's national conditions. According to the survival outcome predicted by the model, the newly diagnosed ER positive / HER2 negative advanced breast cancer was divided into three groups: low, medium, and high risk, which provided an important theoretical basis for further design of randomized controlled clinical research and guidance of individualized precise treatment scheme for different groups in the future.

Conditions

• Breast Cancer

Interventions

Type	Name	Description
OTHER	Establishment of a Survival Prediction Model	a nomogram to predict the survival of patients with ER positive / HER-2 negative advanced breast cancer

Timeline

• Start date: 2020-01-01
• Primary completion: 2021-01-01
• Completion: 2024-12-31
• First posted: 2020-12-24
• Last updated: 2020-12-24

Locations

2 sites across 1 country: China