Trials / Completed
CompletedNCT04683640
Latent Aging Mechanisms in Pain and Sleep
Sleep, Pain and Aging: Potential Underlying Mechanisms
- Status
- Completed
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 33 (actual)
- Sponsor
- University of Florida · Academic / Other
- Sex
- All
- Age
- 45 Years – 100 Years
- Healthy volunteers
- Not accepted
Summary
Chronic pain is a serious public health problem in older adults depending on the pain condition, and the capacity to sleep properly changes with age. Given the potential mechanistic role of GABA (gamma-aminobutyric acid) in both conditions, based on our preliminary data, this proposal will determine the effect of oral GABA administration in sleep quality and pain in older adults with chronic pain and sleep disorders as well as to characterize the potential neurobiological mechanisms involved in both illnesses.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | GABA | Daily oral GABA for 4 weeks |
| DRUG | Placebo | Daily oral Placebo for 4 weeks |
Timeline
- Start date
- 2021-04-02
- Primary completion
- 2024-05-30
- Completion
- 2024-05-30
- First posted
- 2020-12-24
- Last updated
- 2025-07-18
- Results posted
- 2025-07-18
Locations
1 site across 1 country: United States
Regulatory
- FDA-regulated drug study
Source: ClinicalTrials.gov record NCT04683640. Inclusion in this directory is not an endorsement.