NCT04682951

Good Prognosis Factors After Decompressive Craniectomy : a Ten-year Retrospective Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 544 (actual)
• Sponsor: Central Hospital, Nancy, France · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Decompressive craniectomy is a treatment of refractory intracranial hypertension after various etiologies : malignant ischemic stroke, traumatic brain injury, intraparenchymal hemorrhage, aneurysmal subarachnoid hemorrhage, cerebral venous thrombosis. Initially considered as a lifesaving therapy, benefits in terms of survival were shown compared to medical treatment alone. However, despite a better survival, morbidity and poor neurological outcome are frequent among survivors. The objective of the study is to identify initial good neurological outcome factors after decompressive craniectomy in a large series of patients, in order to argue surgical and intensive care decisions, considering expected benefit and quality of life.

Conditions

• Decompressive Craniectomy
• Brain Injuries
• Treatment Outcome

Interventions

Type	Name	Description
PROCEDURE	Decompressive Craniectomy

Timeline

• Start date: 2008-06-01
• Primary completion: 2019-06-30
• Completion: 2020-12-01
• First posted: 2020-12-24
• Last updated: 2020-12-24

Locations

1 site across 1 country: France