NCT04682691

Effect of Metoclopramide Versus Erythromycin on on Gastric Residual Volume

Comparison of the Effect of Metoclopramide Versus Erythromycin on Gastric Residual Volume

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: Cairo University · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

In emergencies, it may be necessary to anaesthetize who are not fully starved and consequently at risk of pulmonary aspiration. Pregnancy are recognized to be at increased risk of aspiration compared with non-pregnancy. Prokinetic agents such as metoclopramide can be used to reduce GRV. Metoclopramide is widely used as a prokinetic agent in adults and is licensed for premedication in pregnancy, but its use may be limited by its potential for producing extrapyramidal side effects. Erythromycin is an effective prokinetic agent in adults but there is no work examining its use for premedication in pregnancy. This study compared the effects of erythromycin and metoclopramide on GRV in full-term pregnant women

Conditions

• Gastric Residual Volume

Interventions

Type	Name	Description
DRUG	Erythromycin (400mg)	oral Erythromycin (400mg)
DRUG	metoclopramide (10mg)	oral metoclopramide (10mg)
DIETARY_SUPPLEMENT	naturally flavored water	naturally flavored water

Timeline

• Start date: 2021-03-01
• Primary completion: 2024-02-05
• Completion: 2024-02-22
• First posted: 2020-12-24
• Last updated: 2025-01-14

Locations

1 site across 1 country: Egypt