NCT04681963

Clinical Characteristics of Acutely Hospitalized Adults With Community-acquired- Pneumonia

Clinical Characteristics of Hospitalized Adults With Community-acquired- Pneumonia at the Emergency Department: A Cross-sectional Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 966 (actual)
• Sponsor: University of Southern Denmark · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

There is no gold standard when diagnosing of pneumonia. The variability of clinical signs and symptoms make it difficult to distinguish pneumonia from other causes of respiratory conditions. Well defined characteristics upon arrival to the emergency department will contribute to the better and quicker diagnosis of community-acquired pneumonia.

Detailed description

Currently, pneumonia diagnosis is primarily based on clinical symptoms such as cough, shortness of breath, chest pain, fever and sputum production, combined with X-ray of the lungs, relevant blood tests and microbiological analysis of sputum samples. The X-ray is an imprecise diagnostic tool, and results from sputum assays are first available after 2 days. In the elderly, pneumonia presents with clinically differing signs such as delirium, malnutrition, and there may be an absence of fever, cough and dyspnea. The physical examination is also challenged by a broad variety of atypical symptoms like headache, dry cough and gastrointestinal symptoms in the form of nausea, vomiting or diarrhea. Our hypothesis is that well-defined clinical characteristics upon arrival to the emergency department will contribute to the better and quicker diagnosis of pneumonia. The aim is to identify the information available upon arrival to the Emergency Department that contributes to diagnosis and prognosis of community-acquired-pneumonia. The objectives are: 1. Identify the information available upon arrival that correlates to the diagnosis of community-acquired pneumonia 2. Identify the information available upon arrival that correlates to severity of community-acquired pneumonia

Conditions

• Pneumonia

Interventions

Type	Name	Description
OTHER	Clinical Assessment within 4 hours of admission	Demographics, Symptoms, Severity scores (Triage at admission, confusion, urea, respiration, blood pressure, age (CURB 65) and pneumonia severity score (PSI), clinical parameters, blood testing, chest x-rays, comorbidities, electro-cardiogram

Timeline

• Start date: 2021-03-01
• Primary completion: 2022-02-28
• Completion: 2022-06-01
• First posted: 2020-12-23
• Last updated: 2022-09-16

Locations

1 site across 1 country: Denmark