Clinical Trials Directory

Trials / Withdrawn

WithdrawnNCT04679324

The Role of Mucosal Microbiome in the Development, Clearance and Recurrence of Clostridioides Difficile Infection

The Role of Mucosal Microbiome in the Development, Clearance and Recurrence of Clostridiodes Difficile Infection

Status
Withdrawn
Phase
Study type
Observational
Enrollment
0 (actual)
Sponsor
Mayo Clinic · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The study is being done to identify types of bacteria associated with the lining of the large intestine in people who have recently been diagnosed with C. difficile infection to determine if there are features associated with development, clearance, and recurrence of disease.

Detailed description

Patients who were recently diagnosed with C. difficile infection will undergo assessment of both before treatment and after completing treatment to study the presence of C. difficile in the colonic mucosa pre as well as assessment for microbiome and patient/clinical factors that may contribute to disease recurrence. Assessment will include sigmoid colon biopsies, blood draw, stool samples and surveys.

Conditions

Timeline

Start date
2019-09-23
Primary completion
2022-08-10
Completion
2022-08-10
First posted
2020-12-22
Last updated
2022-11-29

Source: ClinicalTrials.gov record NCT04679324. Inclusion in this directory is not an endorsement.