Clinical Trials Directory

Trials / Terminated

TerminatedNCT04678557

A Study to Evaluate Safety, Engraftment, and Efficacy of VC-01 in Subjects With T1 Diabetes Mellitus

An Open-Label Phase 1/2 Study to Evaluate the Safety, Engraftment, and Efficacy of VC-01™Combination Product in Subjects With Type 1 Diabetes Mellitus [T1DM]

Status
Terminated
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
31 (actual)
Sponsor
ViaCyte · Industry
Sex
All
Age
18 Years – 65 Years
Healthy volunteers
Not accepted

Summary

VC01-103 will evaluate an experimental combination product, cell replacement therapy intended to provide a functional cure to subjects with Type 1 Diabetes.

Detailed description

This trial will test if VC-01 combination product can be implanted and maintained with safety, tolerability, and efficacy for up to Month 12/Week 52.

Conditions

Interventions

TypeNameDescription
COMBINATION_PRODUCTVC-01 Combination ProductPEC-01 cells loaded into an Encaptra Drug Delivery System

Timeline

Start date
2019-06-25
Primary completion
2021-11-12
Completion
2021-11-19
First posted
2020-12-22
Last updated
2023-10-18
Results posted
2023-10-18

Locations

4 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT04678557. Inclusion in this directory is not an endorsement.