NCT04678063

Validation of Strasbourg Environmental Exposure Chamber ALYATEC in Cat Allergic Subjects With Asthma

Validation Study of the ALYATEC Allergen Exposure Chamber (EEC) by Determining the Concentration of Cat Allergen Inducing Early and/or Late Bronchial Response in Asthmatic Subjects Allergic to Cat

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 31 (actual)
• Sponsor: Alyatec · Industry
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

This is a randomized, double blind, cross-over study designed to determine the concentration of airborne cat allergen inducing bronchial response in asthmatic subjects allergic to cat, during allergen exposures in the Alyatec environmental exposure chamber (EEC). The study was also designed to validate the specificity of the asthmatic reaction induced by exposure to airborne cat allergen in Alyatec EEC.

Conditions

• Allergic Asthma
• Allergy
• Allergy to Cats

Interventions

Type	Name	Description
OTHER	Exposure to Placebo	Patients are exposed to placebo in the EEC
OTHER	Exposure to dose A and dose B of cat allergen	Patients are exposed to dose A and B for successive exposures in the EEC
OTHER	Exposure to a single dose of cat allergen	Patients are exposed to a single dose of cat allergen in the EEC according to the dose selected to achieve the main objective (dose A or B)

Timeline

• Start date: 2017-04-10
• Primary completion: 2017-06-15
• Completion: 2017-07-11
• First posted: 2020-12-21
• Last updated: 2020-12-21

Locations

1 site across 1 country: France