Clinical Trials Directory

Trials / Completed

CompletedNCT04673266

Using Romiplostim to Treat Low Platelet Counts During Chemotherapy in People With Lymphoma

Romiplostim for Prevention of Severe Chemotherapy Induced Thrombocytopenia in Lymphoma Patients - Phase II Study

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
11 (actual)
Sponsor
Memorial Sloan Kettering Cancer Center · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to see if the study drug, romiplostim, helps low platelet count caused by standard chemotherapy treatment for lymphoma. This study will also look at whether romiplostim can prevent the need for chemotherapy dose delays, chemotherapy dose reductions, and platelet transfusions. In addition, we will determine how safe it is to give romiplostim to people with lymphoma who have low platelet count from chemotherapy.

Conditions

Interventions

TypeNameDescription
DRUGRomiplostimAll patients will begin weekly (+/- 2 days) romiplostim at 3 mcg/kg subcutaneously. The romiplostim dose will be titrated, based on weekly CBC/platelet counts.

Timeline

Start date
2020-12-14
Primary completion
2026-04-07
Completion
2026-04-07
First posted
2020-12-17
Last updated
2026-04-13

Locations

7 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT04673266. Inclusion in this directory is not an endorsement.