Clinical Trials Directory

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UnknownNCT04673227

Cytometric Immunodiagnostics of Latent Tuberculosis Infection (LTBI)

Cytometric Immunodiagnostics of Latent Tuberculosis Infection (LTBI) and the Influence of Previous BCG Vaccination - Pilot Study

Status
Unknown
Phase
Study type
Observational
Enrollment
120 (estimated)
Sponsor
Thomayer University Hospital · Academic / Other
Sex
All
Age
4 Years – 70 Years
Healthy volunteers

Summary

TB-reactive immune cells will be tested in a multiparametric flow cytometry to distinguish an immune response for antigens of Mycobacterium spp. in TB disease/latent infection or a reaction after BCG vaccine.

Detailed description

The goal of this project is the verification of current cytometric panel of detection antibodies in a wider panel of stimulative immunodominant antigens for CD4+ and CD8+ T cells in combination with adjuvants 2 in a in vitro activating test.

Conditions

Interventions

TypeNameDescription
DIAGNOSTIC_TESTBlood drawBlood draw and the analysis of blood in laboratory

Timeline

Start date
2020-01-02
Primary completion
2020-05-26
Completion
2022-12-26
First posted
2020-12-17
Last updated
2020-12-17

Locations

2 sites across 1 country: Czechia

Source: ClinicalTrials.gov record NCT04673227. Inclusion in this directory is not an endorsement.