Clinical Trials Directory

Trials / Completed

CompletedNCT04671056

Drug Interaction Study of MGL-3196 With Pioglitazone

A Single Center, Open-Label, Drug Interaction Study of MGL-3196 With Pioglitazone and to Assess Food Effect in Healthy Subjects

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
16 (actual)
Sponsor
Madrigal Pharmaceuticals, Inc. · Industry
Sex
All
Age
19 Years – 55 Years
Healthy volunteers
Accepted

Summary

The purpose of this study is to determine whether the single-dose pharmacokinetics (AUC) of pioglitazone are affected by chronic dosing with MGL-3196 100 mg/day in healthy subjects.

Conditions

Interventions

TypeNameDescription
DRUGMGL-3196MGL-3196 100 mg tablet administered orally in the morning for 13 days
DRUGPioglitazone 15mgPioglitazone 15 mg tablet administered orally on 2 separate days, initially on one day alone and again after MGL-3196 has been dosed to steady-state

Timeline

Start date
2018-11-09
Primary completion
2018-12-11
Completion
2019-01-05
First posted
2020-12-17
Last updated
2020-12-17

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT04671056. Inclusion in this directory is not an endorsement.