NCT04668586

Laser Lithotripsy During URS - Holmium vs Thulium

Laser Lithotripsy During Ureteroscopy - Holmium vs Thulium: A Clinical Prospective Randomized Trial of Effectiveness and Safety

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 120 (actual)
• Sponsor: Haukeland University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aim of the study is to compare URS lithotripsy performed with Holmium:YAG laser and Thulium Fiber Laser. The study is designed as a prospective clinical randomised trial, where the study participants are randomised to either URS with Holmium:YAG laser or URS with Thulium Fiber Laser. The outcomes of the URS procedures are compared for the two treatment arms.

Detailed description

The primary aim of the study is to compare the stone free rate (SFR) following URS lithotripsy with Holmium and Thulium lasers. SFRs will be compared both for ureteral stones, renal stones and ureteral and renal stones in total. Secondary aims are to compare the results of the two lasers in terms of operating times, intraoperative complications, postoperative complications and the rate of post endoscopic JJ-stenting. The study is designed as a prospective clinical randomised trial, where the study participants are randomised to either URS with Holmium:YAG laser or URS with Thulium Fiber Laser. The outcomes of the URS procedures are compared for the two treatment arms.

Conditions

• Urolithiasis

Interventions

Type	Name	Description
DEVICE	Holmium:YAG laser machine	Ureteroscopy with Holmium:YAG laser lithotripsy
DEVICE	Thulium Fiber laser machine	Ureteroscopy with Thulium Fiber laser lithotripsy

Timeline

• Start date: 2021-01-14
• Primary completion: 2021-06-30
• Completion: 2021-10-31
• First posted: 2020-12-16
• Last updated: 2025-03-30
• Results posted: 2025-03-30

Locations

1 site across 1 country: Norway