NCT04667026

Observational Study on Patients With HIV/AIDS(OSPWH)

Observational Study of Antiretroviral Therapy Cohort in Patients With HIV/AIDS

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 15,000 (estimated)
• Sponsor: Guangzhou 8th People's Hospital · Academic / Other
• Sex: All
• Age: 14 Years
• Healthy volunteers: Not accepted

Summary

To establish a follow-up cohort of antiretroviral therapy(ART) for patients with HIV/AIDS, to observe the ART efficacy and adverse reactions, complications in the process of ART, as well as mortality and causes of death, so as to provide basis for further improving ART efficacy and quality of life of the patients.

Detailed description

1. To establish a follow-up cohort of ART for HIV/AIDS patients: follow-up points: before treatment and 1, 2, 3 months after treatment, and every 3 months after treatment. 2. To observe the ART efficacy and adverse reactions: The clinical manifestations, laboratory and auxiliary examination indexes of each follow-up time point was observed in the follow-up cohort, including blood routine, liver function, renal function, blood lipid, blood glucose, urine routine, plasma HIV RNA,CD4 cell count, hepatitis index and syphilis index, etc. If HIV RNA is more than 1000 copies/ml, after treatment for more than 6 months, peripheral blood 10ml should be retained and drug resistance should be detected. 3. To investigate the complications of HIV/AIDS patients before and after ART. 4. To investigate the mortality and causes of death in patients with HIV/AIDS.

Conditions

• HIV Infections

Timeline

• Start date: 2009-01-01
• Primary completion: 2030-12-31
• Completion: 2031-05-31
• First posted: 2020-12-14
• Last updated: 2022-09-14

Locations

1 site across 1 country: China