NCT04664361

Effect of NMN on Muscle Recovery and Physical Capacity in Healthy Volunteers With Moderate Physical Activity

Randomized, Double-blind, Placebo-controlled Clinical Trial of Nicotinamide Mononucleotide on Muscle Recovery and Physical Capacity in Healthy Volunteers With Moderate Physical Activity

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 131 (actual)
• Sponsor: Seneque SA · Industry
• Sex: Male
• Age: 20 Years – 49 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to evaluate the effect of NMN supplementation (250 and 500 mg/day over 38 days) compared to placebo in healthy volunteers with moderate physical activity on muscle recovery, physical capacity, cardiorespiratory recovery, the perception of the arduousness of the effort, the variation in blood lactate levels before and after physical exercise, the perception of the intensity of post-exercise muscle pain (cramps), the body composition and Nicotinamide-Adenine Mononucleotide (NAD+) level in blood.

Conditions

• Physical Activity
• Muscle Recovery

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Nicotinamide mononucleotide	Daily supplementation with NMN at 250 and 500 mg for 38 days in total
OTHER	Placebo	Daily supplementation with placebo for 38 days in total

Timeline

• Start date: 2021-03-09
• Primary completion: 2022-11-10
• Completion: 2023-05-30
• First posted: 2020-12-11
• Last updated: 2024-01-17

Locations

1 site across 1 country: France