NCT04663880

Validation of Strasbourg Environmental Exposure Chamber ALYATEC in Mite Allergic Subjects With Asthma

Validation Study of the ALYATEC Allergen Exposure Chamber by Determining the Concentration of House Dust Mite Allergen Inducing Early and/or Late Bronchial Response in Asthmatic Subjects Allergic to Mite

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 27 (actual)
• Sponsor: Alyatec · Industry
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

This is a randomized, double blind, cross-over study designed to determine the concentration of airborne house dust mite allergen inducing bronchial response in asthmatic subjects allergic to mite, during allergen exposures in the Alyatec environmental exposure chamber (EEC). The study was also designed to validate the specificity of the asthmatic reaction induced by exposure to airborne house dust mite allergen in Alyatec EEC.

Conditions

• Allergic Asthma
• Allergy to House Dust
• Allergy

Interventions

Type	Name	Description
OTHER	Exposure to placebo in EEC	Patients are exposed to placebo (saline solution) in the EEC for 4h maximum
OTHER	Exposure to three concentrations of HDM allergen in EEC	Patients are exposed to different concentrations of airborne HDM allergen (Der p1) in the EEC for 4h maximum
OTHER	Exposure to a single concentration of HDM allergen in EEC	Patients are exposed to a single concentration of airborne HDM allergen (Der p1) in the EEC for 4h maximum

Timeline

• Start date: 2016-08-30
• Primary completion: 2017-01-23
• Completion: 2017-02-15
• First posted: 2020-12-11
• Last updated: 2020-12-11

Locations

1 site across 1 country: France