NCT04660526

RACE-CARS - RAndomized Cluster Evaluation of Cardiac ARrest Systems

RAndomized Cluster Evaluation of Cardiac ARrest Systems

• Status: Enrolling By Invitation
• Phase: N/A
• Study type: Interventional
• Enrollment: 20,000 (estimated)
• Sponsor: Duke University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

RACE-CARS is a real-world cluster-randomized trial designed to evaluate a multifaceted community and health systems intervention aimed to improve outcomes of out-of-hospital cardiac arrest. RACE-CARS will enroll 50 counties in North Carolina that are estimated to have a total of approximately 20,000 patients with cardiac arrest over a 4-year intervention period. County "clusters" will be randomized in a 1:1 ratio to intervention versus usual care. The trial duration is 7 years, which includes a 6-month start-up (including recruitment and randomization) period, a 12-month intervention training phase, a 4-year intervention period, a 12-month follow-up for to assess quality of life in survivors of OHCA, and a 6-month close-out and data analysis period.

Conditions

• Cardiac Arrest

Interventions

Type	Name	Description
OTHER	Rapid cardiac arrest recognition that triggers immediate priority EMS/first responder dispatch by 911 operators	EMS first responders will recognize cardiac arrest and respond immediately, increasing time to dispatch
OTHER	Systematic bystander resuscitation instruction by 911 operators	911 operators will be able to describe how to administer CPR over the phone.
OTHER	Comprehensive community training of lay people in CPR and AED use.	Training of lay people regarding CPR and AED use.
OTHER	Optimized first responder performance including earlier use of AEDs.	First responders will recognize where AEDs are located and use them appropriately

Timeline

• Start date: 2022-07-01
• Primary completion: 2027-06-30
• Completion: 2027-06-30
• First posted: 2020-12-09
• Last updated: 2025-04-30

Locations

1 site across 1 country: United States