NCT04660006

Diabetic Retinopathy and OCT-A Changes Post-cataract Surgery

Optical Coherence Tomography Angiography Changes Post-cataract Surgery in Patients With and Without Diabetic Retinopathy

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 170 (estimated)
• Sponsor: Uptown Eye Specialists · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

The purpose of this study is to use optical coherence tomography angiography (OCT-A) to compare retinal vasculature after uncomplicated cataract surgery in patients with and without diabetic retinopathy.

Detailed description

Patients undergoing cataract surgery who provided informed consent were enrolled in the study. There were three comparison groups: control, diabetic retinopathy (DR) and diabetic macular edema (DME) groups. Optical coherence tomography angiography (OCT-A) scans measuring retinal thickness, vessel density, perfusion density, and foveal avascular zone were obtained at baseline and postoperative week one, month one and month three.

Conditions

• Cataract
• Diabetic Retinopathy
• Macular Edema Due to Diabetes Mellitus

Interventions

Type	Name	Description
PROCEDURE	Cataract surgery	Patients undergoing uneventful cataract surgery were recruited to this study if they met the inclusion criteria of the three groups. Postoperative retinal vasculature measures, as recorded by the optical coherence tomography angiography imaging technique, were compared to baseline measures.

Timeline

• Start date: 2019-05-27
• Primary completion: 2021-07-01
• Completion: 2021-07-01
• First posted: 2020-12-09
• Last updated: 2020-12-09

Locations

1 site across 1 country: Canada