Trials / Completed
CompletedNCT04659980
Preventing Taxane-related Peripheral Neuropathy, Pain and Nail Toxicity: A Prospective Self-controlled Trial Comparing Hilotherapy With Frozen Gloves in Early Breast Cancer
Hilotherapy vs Frozen Gloves for Preventing Taxane-related Peripheral Neuropathy, Pain and Nail Toxicity in Breast Cancer
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 62 (actual)
- Sponsor
- Universitaire Ziekenhuizen KU Leuven · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The prevention of taxane-related toxicities at the extremities is highly important for patients' treatment and quality-of-life. Unlike standard cryotherapy with frozen gloves, hilotherapy produces cooling at a constant temperature. Comparative data with frozen gloves are unavailable. This prospective self-controlled study explores the efficacy of hilotherapy at the right hand and foot compared to frozen gloves at the left in patients with early breast cancer treated with weekly paclitaxel 80 mg/m² or three-weekly docetaxel 75 mg/m².
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | hilotherapy | continuous cooling of hands and feet at a constant temperature |
| DEVICE | frozen gloves | cooling of hands and feet using frozen gloves |
Timeline
- Start date
- 2019-06-20
- Primary completion
- 2020-11-20
- Completion
- 2020-11-20
- First posted
- 2020-12-09
- Last updated
- 2020-12-11
Locations
1 site across 1 country: Belgium
Source: ClinicalTrials.gov record NCT04659980. Inclusion in this directory is not an endorsement.