NCT04654494

Colorectal Cancer in Crohn's Disease

Colorectal Cancer in Crohn's Disease: Long Term Outcomes of Different Surgical Procedures

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 70 (estimated)
• Sponsor: University of Rome Tor Vergata · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Retrospective multicentre study. All patients with a diagnosis of Crohn's disease (CD) and operated for colorectal cancer (CRC) between 01/01/2010 and 01/01/2020 will be included in the dataset. Data will include preoperative, intraoperative and postoperative variables, with long term follow up when feasible. The study will focus on a comparison between patients treated with total proctocolectomy (TPC) and patients treated with subtotal colectomy (STC) or segmental resection (SR). Primary endpoints will be oncologic outcomes, postoperative morbidity and mortality. Secondary endpoints include quality of life (QoL).

Conditions

• Crohn Disease
• Colorectal Cancer
• Inflammatory Bowel Diseases

Interventions

Type	Name	Description
PROCEDURE	Total proctocolectomy	excision of the whole large bowel including colon and rectum and end ileostomy fashioning
PROCEDURE	Total colectomy	excision of the colon with preservation of the rectum
PROCEDURE	Segmental colectomy	excision of a segment of colon

Timeline

• Start date: 2020-07-01
• Primary completion: 2021-01-01
• Completion: 2021-01-01
• First posted: 2020-12-04
• Last updated: 2020-12-08

Locations

1 site across 1 country: Italy