NCT04653181

Preoperative i.v. Iron Substitution in Patients With Colon Cancer

Preoperative i.v. Iron Substitution in Patients With Colon Carcinoma and Iron-deficiency Anemia

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 514 (estimated)
• Sponsor: Helsinki University Central Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

About 70% of colon cancer patients are anemic. Preoperative anemia in patients with colorectal cancer is associated with both impaired disease-free survival and overall survival. The purpose of this study is to compare the effects of preoperative iv iron substitution on postoperative recovery in preoperatively anemic (male Hb \<130, female Hb \<120) and iron deficient colon cancer patients in a prospective setup. As a primary outcome, the effect of iv-iron substitution on postoperative complications is investigated.

Detailed description

Randomized preoperative iron substitution for patient with iron deficient anemia

Conditions

• Colon Cancer

Interventions

Type	Name	Description
DRUG	Ferric carboxymaltose	Iron-arm treated with Ferric carboxymaltose, non-iron arm without

Timeline

• Start date: 2020-10-01
• Primary completion: 2024-12-31
• Completion: 2025-12-31
• First posted: 2020-12-04
• Last updated: 2024-02-29

Locations

1 site across 1 country: Finland