NCT04652609

Preventing Chemotherapy-induced Peripheral Neuropathy Using PRESIONA Exercise Program

Prevention of Chemotherapy-induced Peripheral Neuropathy With Therapeutic Exercise and Blood Flow Restriction Using PRESIONA Program

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 25 (estimated)
• Sponsor: Universidad de Granada · Academic / Other
• Sex: Female
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to determinate if therapeutic exercise with blood flow restriction (BFR) during neoadjuvant chemotherapy potentialy neurotoxic could prevent the onset of chemotherapy induced peripheral neuropathy (CIPN) comparing to usual care.

Detailed description

CIPN is a side effect of cancer therapies that nowadays has no solution, so our intention is to carry out a preventive therapy against the onset of CIPN. The nature of the studies that try to prevent is very diverse, but one of the wide tools is therapeutic exercise. In this case we intend to combine therapeutic exercise with BFR to obtain a pre-conditioning effect that protects intraepidermal fibers from exposure to the chemotherapy.

Conditions

• Breast Neoplasm

Interventions

Type	Name	Description
OTHER	PRESIONA	Aerobic and strength exercise combined with restricction blood flow cuffs during chemotherapy treatment

Timeline

• Start date: 2021-01-01
• Primary completion: 2025-01-01
• Completion: 2027-01-01
• First posted: 2020-12-03
• Last updated: 2025-11-18

Locations

1 site across 1 country: Spain