Clinical Trials Directory

Trials / Terminated

TerminatedNCT04652570

Efficacy and Safety of VB119 in Subjects With Membranous Nephropathy

A Phase 1b/2a Study of VB119 in Adult Subjects With Primary Membranous Nephropathy

Status
Terminated
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
6 (actual)
Sponsor
Tenet Medicines · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This study is a Phase 1b/2a, open-label, sequential-cohort, dose escalation, and dose expansion study to evaluate the safety, tolerability, PK, and PD of VB119 in subjects with primary MN

Conditions

Interventions

TypeNameDescription
DRUGVB119Humanized, immunoglobin (Ig) G1 monoclonal antibody (mAb) to be administered as intravenous infusion at multiple timepoints during the study.

Timeline

Start date
2021-05-05
Primary completion
2023-11-21
Completion
2024-08-15
First posted
2020-12-03
Last updated
2026-02-12

Locations

4 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT04652570. Inclusion in this directory is not an endorsement.