Trials / Completed
CompletedNCT04652219
CART Therapy in GUCY2C-positive Digestive Tract Tumors
Clinical Study on the Safety and Efficacy of CART Cells in the Treatment of Advanced GUCY2C-positive Digestive Tract Tumors
- Status
- Completed
- Phase
- EARLY_Phase 1
- Study type
- Interventional
- Enrollment
- 1 (actual)
- Sponsor
- Weijia Fang, MD · Academic / Other
- Sex
- All
- Age
- 18 Years – 70 Years
- Healthy volunteers
- Not accepted
Summary
Ict-gc is an open, single-center study to evaluate the safety and efficacy of CAR-T-targeted therapy in patients with advanced gastrointestinal tumors.
Detailed description
The primary objective of phase 1 is to evaluate the safety of CART regimens. The primary objective of phase 2 is to evaluate the efficacy of CART, as measured by objective response rate in subjects with colorectal cancer. Secondary objectives will include assessing the safety and tolerability of CART and additional efficacy endpoints.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BIOLOGICAL | gucy2c cart cells | Patients with advanced malignant gastrointestinal tumors were injected with CART cells |
Timeline
- Start date
- 2020-10-10
- Primary completion
- 2021-10-09
- Completion
- 2021-10-09
- First posted
- 2020-12-03
- Last updated
- 2023-07-17
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT04652219. Inclusion in this directory is not an endorsement.