NCT04651322

Quantified Analysis of Neuronal Recovery Using Myelin Imaging After Robot Assisted Upper Arm Training in Subacute Stroke Patients

Quantified Analysis of Neuronal Recovery Using Myelin Imaging After Robot Assisted Upper Arm Training in Subacute Stroke Patients: Randomized Controlled Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (estimated)
• Sponsor: Yonsei University · Academic / Other
• Sex: All
• Age: 20 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

* Quantitative assessment method developed for brain plasticity through disability rehabilitation using a brain imaging technique. * Development of brain imaging technology to improve understanding of brain plasticity during rehabilitation and to improve the efficiency of rehabilitation treatment for people with brain injury. ○ Development of the latest brain function image analysis algorithm and data processing technology * Development of new technology for imaging brain plasticity in addition to existing functional imaging technology and diffuse imaging technology (Example: Myelinated brain imaging technology, susceptibility imaging (SWI) technology) * Development of image reconstruction software technology using new image technology * Multi-image and repeated shot data processing technology, wheat analysis technology development (Example: 3D registration technology, automated segmentation technology) * Conducted clinical research on clinical quantitative evaluation of brain plasticity due to rehabilitation treatment * Recruitment of a group of patients for pursuing plasticity through rehabilitation among stroke patients (estimating the number of sample patients by setting a specific patient group and analyzing statistical power) * Image-based brain change analysis through patient rehabilitation and before and after imaging * Comparative analysis through securing a control group and activating the control group. Derivation of clinical relevance through comparison with rehabilitation process

Conditions

• Stroke

Interventions

Type	Name	Description
DEVICE	upper robot Robot assisted upper arm training(RAT)	The training group received an additional upper robot Robot assisted upper arm training(RAT) with Armeopower® 5 times per week for 4weeks. \*Robot Assisted Arm training + Conventional occupational therapy
BEHAVIORAL	Conventional therapy	The control group received the usual conventional therapy \*Only Conventional occupational therapy

Timeline

• Start date: 2019-03-01
• Primary completion: 2021-06-01
• Completion: 2021-06-01
• First posted: 2020-12-03
• Last updated: 2020-12-03

Locations

1 site across 1 country: South Korea