NCT04650763

Bone Healing in Immediate Dental Implants

Effect of PRP on Bone Healing in Immediate Implants Analyzed by CBCT

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 12 (actual)
• Sponsor: CMH Lahore Medical College and Institute of Dentistry · Academic / Other
• Sex: All
• Age: 20 Years – 50 Years
• Healthy volunteers: Accepted

Summary

To study the effect of platelet-rich plasma concentrate on marginal bone loss and bone mineral density in immediate implant placement through CBCT.

Detailed description

12 subjects were equally categorized into two groups. Group, I was the control group; whereas, the subjects in Group II received Platelet Rich Plasma (PRP) therapy. All subjects were given a standard treatment with single implant system. Inserted implants were analyzed through Cone Beam Computerized Tomography (CBCT). Records were registered at the baseline, at 12th week before functional loading and 26th week after functional loading.

Conditions

• Alveolar Bone Loss
• Platelet Rich Plasma

Interventions

Type	Name	Description
BIOLOGICAL	PRP injection	PRP was prepared using patient's blood and mixed with saline or mixture of calcium chloride and thrombin to form a liquid solution; in order to inject at the surgical site after placement of implant.
DEVICE	Automated blood cell separator to extract PRP	Blood was withdrawn from antecubital vein and mixed with anticoagulant. Blood sample was then centrifuged to obtain platelet rich plasma which was injected at surgical site after implant placement.

Timeline

• Start date: 2017-10-02
• Primary completion: 2018-03-30
• Completion: 2018-03-30
• First posted: 2020-12-03
• Last updated: 2020-12-03

Locations

1 site across 1 country: Pakistan

Regulatory

• FDA-regulated device study