NCT04643444

Police COVID-19 Serosurvey

Police Officer COVID-19 Seroprevalence Survey in the Canton of Bern, Switzerland

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 1,024 (actual)
• Sponsor: University of Bern · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The investigators aim to determine the immune status of the employees of the cantonal police of Bern against SARS-CoV-2 over a period of 1 year, and to investigate the risk profile of the study participants and their risk of SARS-CoV-2 exposure in their working and private environments, as well as to evaluate the use of personal protective equipment at potential exposure instances.

Detailed description

i) To determine the extent of infection with seroprevalence data in the special population of police officers of the canton Bern. ii) To determine risk factors for infection by comparing the proportion of seropositivity (infected versus noninfected individuals). The investigators hypothesize that police officers with fieldwork activity will have a higher seroprevalence than will office and administration personnel. The investigators hypothesize that working in the city of Bern will be associated with a higher seroprevalence than will working in other geographic areas of the canton (i.e. rural area). iii) To monitor COVID-19 antibody titres and neutralizing capacity over time and to associate them with reinfection rates and infection-free intervals in police officers after accidental contact with a proven COVID-19 case. The investigators hypothesize that in seropositive individuals, there will be a decreasing dynamic of antibody titres over the one-year study period, and hence, a decrease of neutralizing capacity.

Conditions

• SARS-CoV-2 Infection
• Volunteers
• Healthy

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Blood sampling	Testing for the presence of SARS-CoV-2 antibodies
OTHER	Online Questionnaire	Questions on working place, risk profiles and PPE

Timeline

• Start date: 2021-02-09
• Primary completion: 2022-06-30
• Completion: 2022-06-30
• First posted: 2020-11-25
• Last updated: 2025-11-21

Locations

1 site across 1 country: Switzerland