NCT04642963

Stereotactic Management of Arrhythmia - Radiosurgery in Treatment of Ventricular Tachycardia

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 11 (actual)
• Sponsor: Maria Sklodowska-Curie National Research Institute of Oncology · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Prospective single-arm study investigating the safety of non-invasive cardiac radiosurgery for the treatment of ventricular tachycardia (VT).

Detailed description

The standard of care for the treatment of Ventricular Tachycardia (VT) comprises of pharmacotherapy, ICD implantation and electrophysiology-guided catheter ablation. The treatment, however, is associated with a relatively high risk of VT recurrence. Given the limited therapeutic options and significant impact on patients quality of life, non-invasive cardiac radiosurgery has been recently gaining popularity in scientific literature as a viable alternative to salvage catheter ablations. Considering the scarcity of data from prospective trials and concern about the safety of the treatment method, this trial seeks to determine whether Stereotactic Management of Arrhythmia - Radiosurgery in Treatment of Ventricular Tachycardia (SMART-VT) meets the expected safety requirements for clinical use.

Conditions

• Ventricular Tachycardia

Interventions

Type	Name	Description
RADIATION	Cardiac Radiosurgery	Non-invasive delivery of ablative radiotherapy dose to the arrhythmia substrate.

Timeline

• Start date: 2020-09-11
• Primary completion: 2023-01-10
• Completion: 2023-01-10
• First posted: 2020-11-24
• Last updated: 2023-03-15

Locations

2 sites across 1 country: Poland