Clinical Trials Directory

Trials / Completed

CompletedNCT04642547

Lenvatinib Combined With Gefitinib in the Treatment of Lenvatinib-resistant Hepatocellular Carcinoma

A Prospective Clinical Study of Lenvatinib Combined With Gefitinib in the Treatment of Lenvatinib-resistant Hepatocellular Carcinoma

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
30 (actual)
Sponsor
RenJi Hospital · Academic / Other
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

This is a prospective clinical study aiming to tests the safety and efficacy of lenvatinib in combination with gefitinib in people with lenvatinib resistant hepatocellular carcinoma. This study will help find out if lenvatinib and gefitinib is a safe and useful combination for treating patients with lenvatinib resistant hepatocellular carcinoma.

Conditions

Interventions

TypeNameDescription
DRUGLenvatinib and GefitinibFirst week: Gefitinib: 125mg/day, oral; Lenvatinib: 8mg/day (weight ≤ 60Kg) or 12mg/day (weight \> 60Kg), oral. One week later: Gefitinib: 250mg/day, oral; Lenvatinib: 8mg/day (weight ≤ 60Kg) or 12mg/day (weight \> 60Kg), oral.

Timeline

Start date
2020-12-02
Primary completion
2023-03-31
Completion
2023-03-31
First posted
2020-11-24
Last updated
2023-08-01

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT04642547. Inclusion in this directory is not an endorsement.

Lenvatinib Combined With Gefitinib in the Treatment of Lenvatinib-resistant Hepatocellular Carcinoma (NCT04642547) · Clinical Trials Directory