NCT04640428

COVID-19 Stroke Apical Lung Examination Study

COVID-19 Stroke Apical Lung Examination Study - A Multi-centre Prospective Study

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 2,000 (estimated)
• Sponsor: King's College Hospital NHS Trust · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Multi-centre prospective study evaluating computed tomography angiography studies performed for stroke patients as a diagnostic and prognostic imaging biomarker.

Detailed description

Diagnosis of coronavirus disease 2019 (COVID-19) relies on clinical features and reverse-transcriptase polymerase chain reaction (RT-PCR) testing. The latter is constrained by limited sensitivity and a timescale of hours to yield results, with no point-of-care test widely available. A dedicated computed tomography study of the chest is likely to be more sensitive than RT-PCR for COVID-19. Carotid computed tomography angiography (CTA) is a routine acute stroke investigation and includes the lung apices. We aim to assess the lung apices on CTA for ground glass opacification and compare this with COVID-19 RT-PCR test results and clinical outcome measures.

Conditions

• Covid19
• Stroke, Acute
• Stroke, Ischemic
• Stroke Hemorrhagic

Timeline

• Start date: 2020-07-10
• Primary completion: 2021-10-31
• Completion: 2021-10-31
• First posted: 2020-11-23
• Last updated: 2021-05-27

Locations

12 sites across 1 country: United Kingdom