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Active Not RecruitingNCT04640025

A Rollover Study to Provide Continued Treatment for Participants Previously Enrolled in Studies of Itacitinib

A Phase 2, Open-Label, Multicenter, Rollover Study to Provide Continued Treatment for Participants Previously Enrolled in Studies of Itacitinib (INCB039110)

Status
Active Not Recruiting
Phase
Phase 2
Study type
Interventional
Enrollment
18 (actual)
Sponsor
Incyte Corporation · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This is a mutli-center open-label study to provide continued supply of itacitinib to participants from the following Incyte-sponsored studies of itacitinib: INCB39110-209, INCB39110-213, INCB39110-214, INCB39110-230, and 39110-309. Eligible participants will receive treatment with itacitinib as per the treatment dose and schedule they received in the study in which they were originally enrolled. The original study is referred to as the "parent protocol". Participants who receive itacitinib in this study may continue treatment as long as the regimen is tolerated, the participant is deriving clinical benefit (in the opinion of the investigator), and the participant does not meet discontinuation criteria.

Conditions

Interventions

TypeNameDescription
DRUGitacitinibParticipants will self-administer itacitinib orally using intact tablets with water and without regard to food.

Timeline

Start date
2021-03-10
Primary completion
2026-06-22
Completion
2026-06-22
First posted
2020-11-23
Last updated
2025-12-10

Locations

21 sites across 9 countries: United States, Austria, Belgium, Canada, Germany, Greece, Israel, Italy, Spain

Regulatory

Source: ClinicalTrials.gov record NCT04640025. Inclusion in this directory is not an endorsement.