Clinical Trials Directory

Trials / Withdrawn

WithdrawnNCT04637555

Open-label Extension Study for CLCZ696G2301 (PARADISE-MI)

A Multicenter Study to Evaluate the Long-term Safety and Tolerability of Open-label LCZ696 in Patients With Acute Myocardial Infarction Who Previously Participated in CLCZ696G2301 (PARADISE-MI)

Status
Withdrawn
Phase
Phase 3
Study type
Interventional
Enrollment
0 (actual)
Sponsor
Novartis Pharmaceuticals · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to collect long-term safety and tolerability data of LCZ696 and to provide open-label LCZ696 to eligible participants who completed CLCZ696G2301 study (PARADISE-MI) if LCZ696 is shown to have a positive benefit-risk profile in comparison to ramipril in reducing risk of cardiovascular (CV) mortality and development of heart failure in participants enrolled in the PARADISE-MI study.

Conditions

Interventions

TypeNameDescription
DRUGsacubitril/valsartanLCZ696 (sacubitril/valsartan) tablet will be available in 24/26 mg, 49/51 mg and 97/103 mg, respectively

Timeline

Start date
2021-05-26
Primary completion
2023-06-01
Completion
2023-06-01
First posted
2020-11-19
Last updated
2021-11-26

Regulatory

Source: ClinicalTrials.gov record NCT04637555. Inclusion in this directory is not an endorsement.