NCT04637321

The Incidence and Risk Factors for Clostridioides Difficle Infection in Solid Organ Transplant Recipients

Everyone Poops: An Evaluation of the Incidence and Risk Factors for Clostridioides Difficle Infection in Solid Organ Transplant Recipients

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 585 (actual)
• Sponsor: Methodist Health System · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

2.1. Study Objectives * Primary Objective(s) * Identify the incidence and risk of CDI within one year after kidney, liver, and/or pancreas transplant * Secondary Objective(s) * Identify the risk factors for recurrent CDI post-transplant in patients who were diagnosed with a CDI within one year prior to Solid Organ Transplant * Evaluate the impact of CDI on graft survival following Solid Organ Transplant

Detailed description

* Single center, retrospective cohort chart review study design * Data will be collected on all liver, kidney, pancreas and combined transplant recipients who received their graft(s) from April 1, 2015 to July 31, 2018 * Will analyze outcomes from April 1, 2014 to July 31, 2019 * Patient list will be generated in Epic and Meditech * All data will be obtained from Epic and Meditech * All data will be collected retrospectively after the patient is discharged from the hospital

Conditions

• Infection in Solid Organ Transplant Recipients

Interventions

Type	Name	Description
PROCEDURE	Solid organ transplant	Data will be collected on all liver, kidney, pancreas and combined transplant recipients who received their graft(s) from April 1, 2015 to July 31, 2018

Timeline

• Start date: 2019-11-04
• Primary completion: 2020-08-07
• Completion: 2020-08-07
• First posted: 2020-11-19
• Last updated: 2022-02-04

Locations

1 site across 1 country: United States