Trials / Completed
CompletedNCT04637165
Exploring the Immunology of Sarcoidosis
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 9 (actual)
- Sponsor
- Hull University Teaching Hospitals NHS Trust · Other Government
- Sex
- All
- Age
- 18 Years – 85 Years
- Healthy volunteers
- Not accepted
Summary
In sarcoidosis, over activity of parts of the immune system drives the accumulation of granulomas (collections of immune cells) in affected parts of the body. To facilitate development of effective and safe treatment options in the future it will be vital to understand how and why the immune system becomes over active. The aim of this research is to work towards this goal by studying cells of the immune system and the molecular pathways inside these cells that control how they behave. This will be achieved by analysing patterns of proteins and RNA (the code used to tell cells which proteins to produce) in immune cells present in blood samples and tissue biopsies from people with sarcoidosis.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | This is a non-interventional study | This is a non-interventional study |
Timeline
- Start date
- 2019-11-11
- Primary completion
- 2022-12-31
- Completion
- 2023-12-31
- First posted
- 2020-11-19
- Last updated
- 2024-10-02
Locations
1 site across 1 country: United Kingdom
Source: ClinicalTrials.gov record NCT04637165. Inclusion in this directory is not an endorsement.