Clinical Trials Directory

Trials / Unknown

UnknownNCT04634747

Phase 2 Study to Evaluate PVX-410 + Pembrolizumab + Chemotherapy for Metastatic, PD-L1+ Triple-Negative Breast Cancer

A Single-Arm, Open-Label, Multi-Center Phase II Study to Evaluate the Combination of PVX-410 + Pembrolizumab + Chemotherapy for Frontline Therapy of Metastatic, PD-L1+ Triple-Negative Breast Cancer (TNBC) in HLA-A2-Positive Patients

Status
Unknown
Phase
Phase 2
Study type
Interventional
Enrollment
53 (estimated)
Sponsor
OncoPep, Inc. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Evaluating the combination of the investigational, multi-peptide cancer vaccine PVX-410 in combination with pembrolizumab and chemotherapy in treatment naive patients with metastatic, triple negative breast cancer who are PDL1 and HLA A2 positive.

Conditions

Interventions

TypeNameDescription
DRUGPVX-410PVX-410 in combination with pembrolizumab and chemotherapy

Timeline

Start date
2022-04-30
Primary completion
2023-04-01
Completion
2025-04-01
First posted
2020-11-18
Last updated
2022-04-20

Regulatory

Source: ClinicalTrials.gov record NCT04634747. Inclusion in this directory is not an endorsement.