NCT04633720

Exploration of the Appropriate Combination of Positive End Expiratory Pressure and Tidal Volume Using the Intratidal Compliance Volume Profile in Children

Exploration of the Appropriate Combination of Positive End Expiratory Pressure and Tidal Volume Using the Intratidal Compliance-volume Profile in Children

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 43 (actual)
• Sponsor: Seoul National University Hospital · Academic / Other
• Sex: All
• Age: 1 Month – 6 Years
• Healthy volunteers: Not accepted

Summary

In children under 6 years of age undergoing regular surgery during general anesthesia, the intratidal compliance profile is evaluated when different tidal volumes are applied at different positive end expiratory pressures. Then determine the most appropriate combination of positive end-tidal pressure and tidal volume.

Conditions

• Respiratory Compliance

Interventions

Type	Name	Description
OTHER	Changes in positive end-expiratory pressure and tidal volume	When the patient is in the supine position 10 minutes after induction of anesthesia, the following 4 mechanical ventilator settings are applied to the patients in order. Positive end-expiratory pressure 8 cmH2O, tidal volume 8 ml/kg Positive end-expiratory pressure 10 cmH2O, tidal volume 5 ml/kg Positive end-expiratory pressure 10 cmH2O, tidal volume 8 ml/kg Positive end-expiratory pressure 12 cmH2O, tidal volume 5 ml/kg

Timeline

• Start date: 2020-12-02
• Primary completion: 2021-04-30
• Completion: 2021-05-30
• First posted: 2020-11-18
• Last updated: 2022-05-05

Locations

1 site across 1 country: South Korea