NCT04632563

Prevalence of Musculoskeletal Symptoms in the Cambridge NIHR BioResource

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 5,000 (estimated)
• Sponsor: Cambridge University Hospitals NHS Foundation Trust · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Musculoskeletal diseases, such as osteoarthritis, represent a large proportion of the global burden of disease with hip and knee osteoarthritis alone being the 11th greatest cause of disease burden. The purpose of this study is to determine the level of musculoskeletal symptoms in members of the Cambridge National Institute for Health Research (NIHR) BioResource and see if this is associated with their possession of genetic markers that have been identified as being associated with osteoarthritis. This will allow us to determine the real level of musculoskeletal symptoms in this large cohort of volunteers and provide basic information that could be used to facilitate further musculoskeletal research in the NIHR BioResource population.

Detailed description

All active members of the Cambridge NIHR BioResource will be approached. They will be sent an email outlining the purpose of the study and asking that if they would like to take part to please complete the online questionnaire which will be linked to in the email. For those individuals who agree to participate and complete the questionnaire, the Cambridge NIHR BioResource will provide the genetic marker information it already holds for specific markers that are known to be associated with osteoarthritis.

Conditions

• Musculoskeletal Diseases
• Musculoskeletal Injury

Interventions

Type	Name	Description
OTHER	Questionnaire including MSK-HQ (Musculoskeletal Health Questionnaire)	A questionnaire regarding musculoskeletal past medical history and current symptoms.

Timeline

• Start date: 2020-11-01
• Primary completion: 2021-04-01
• Completion: 2021-08-01
• First posted: 2020-11-17
• Last updated: 2020-11-17