Trials / Completed
CompletedNCT04630938
Effects of Anaesthesia on Inflammatory Markers
Effects of Anesthetics on Inflammatory Markers in Patients Undergoing Abdominal Surgeries.
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 81 (actual)
- Sponsor
- Assiut University · Academic / Other
- Sex
- All
- Age
- 18 Years – 55 Years
- Healthy volunteers
- Not accepted
Summary
undertake confidently both open and laparoscopic cholecystectomy. Major types of body injuries surgical or accidental; evoke a temporary, yet predictable systemic inflammatory response caused by hormonal, immunological and metabolic mediators. This inflammatory response is essential for tissue repair and has evolved to maximize the organisms' healing potential. In healthy individuals the inflammatory response to major surgery is well balanced consisting of pro- and anti-inflammatory mediators. The severity of injury, the occurrence of surgical complications and its accompanying level of stress may hinder the balance of the inflammatory response6.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Morphine Sulfate | intrathecal morphine will be added to anaesthetics |
| DRUG | morphine+lidocaine | local anesthetic will be infused intravenously |
| DRUG | Saline | intravenous saline infusion |
Timeline
- Start date
- 2020-10-24
- Primary completion
- 2021-10-01
- Completion
- 2021-10-30
- First posted
- 2020-11-16
- Last updated
- 2022-02-24
Locations
1 site across 1 country: Egypt
Source: ClinicalTrials.gov record NCT04630938. Inclusion in this directory is not an endorsement.