Trials / Recruiting
RecruitingNCT04630613
NOX4 and Related Biomarkers in ADPKD
NOX4, Mitochondria and Related Biomarkers in Autosomal Dominant Polycystic Kidney Disease
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 60 (estimated)
- Sponsor
- Mayo Clinic · Academic / Other
- Sex
- All
- Age
- 15 Years – 40 Years
- Healthy volunteers
- Not accepted
Summary
To determine the value of NOX4, markers of mitochondria injury and function, and oxidative stress as real-time biomarkers to assess disease severity in patients with early autosomal dominant polycystic kidney disease (ADPKD).
Detailed description
This will be a cross sectional study and will include male and female, young (15-40-years) well characterized patients with early (eGFR\>70mL/min/1.73m2) ADPKD. Patients with different classes of disease severity will be selected using the ADPKD imaging classification. The study will include 60 class-1 (A-E) patients (N=12 per each sub-class).
Conditions
Timeline
- Start date
- 2020-07-21
- Primary completion
- 2026-12-01
- Completion
- 2027-01-01
- First posted
- 2020-11-16
- Last updated
- 2026-01-09
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT04630613. Inclusion in this directory is not an endorsement.