NCT04630431

Understanding Challenges, Behavioral Patterns, and Preferences Toward Participation in Clinical Trials in Minority Patient Populations: Development of a Personalized Clinical Trial Educational Platform to Increase Participation in Clinical Trials Among Underserved Cancer Patients

Understanding the Challenges, Behavioral Patterns, and Preferences Towards Participation in Clinical Trials in Minority Patient Populations: Development and Validation of a Personalized Clinical Trial Educational Platform to Boost Participation Among Underserved Cancer Patients

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 590 (actual)
• Sponsor: Mayo Clinic · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This clinical trial investigates the challenges, behavioral patterns, and preferences towards participation in clinical trials in minority patient populations in order to develop a personalized clinical trial educational platform to increase participation in clinical trials among underserved cancer patients. Learning more about patients' understanding of clinical trials may help identify barriers that limit patient's participation. Information gathered from this trial will be used to develop educational materials that may aid minority patients in overcoming barriers to participating in clinical trials. A personalized clinical trial educational platform may help increase participation in clinical trials among minority populations.

Detailed description

PRIMARY OBJECTIVES: I. To understand and document patient preferences, understanding, and attitudes regarding clinical trials. II. To compare patient attitudes regarding clinical trials among cancer patients belonging to different racial/ethnic groups. III. To establish the magnitude of existing knowledge gap relating to clinical trials among underserved cancer patients and the extent of improvement with a personalized educational approach. IV. To determine how a personalized educational approach impacts enrollment in clinical trials of underserved cancer patients. OUTLINE: PART I: Patients complete a questionnaire about their preferences, understanding, and attitudes regarding clinical trials. Patients also have their medical records reviewed. PART II: Patients are randomized to 1 of 2 arms. ARM A: Patients undergo clinical trial education via a video and educational booklet and then standard of care follow-up on study. ARM B: Patients undergo clinical trial education via a video and educational booklet and then undergo patient navigation with active clinical trial matching and receive clinical trial information through the electronic medical record portal on study.

Conditions

• Hematopoietic and Lymphoid Cell Neoplasm
• Malignant Solid Neoplasm

Interventions

Type	Name	Description
OTHER	Best Practice	Undergo standard of care follow-up
OTHER	Educational Intervention	Undergo clinical trial education via a video and educational booklet
OTHER	Electronic Health Record Review	Review of medical record
BEHAVIORAL	Patient Navigation	Undergo clinical trial navigation
OTHER	Questionnaire Administration	Complete questionnaire

Timeline

• Start date: 2019-10-15
• Primary completion: 2026-10-15
• Completion: 2026-10-15
• First posted: 2020-11-16
• Last updated: 2025-12-17

Locations

3 sites across 1 country: United States