NCT04628078

LAAC-registry: Clinical Outcome After Echocardiography-guided LAA-closure

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 1,000 (estimated)
• Sponsor: Insel Gruppe AG, University Hospital Bern · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

The study aims at comparing, in a large cohort of consecutive clinically indicated left atrial appendage closure, clinical and imaging outcomes between different subpopulations.

Detailed description

Percutaneous left atrial appendage closure (LAAC) has established itself in clinical practice as a safe and efficient therapeutic option for atrial fibrillation patients with a relative/absolute contraindication to oral anticoagulation. The purpose of this observational study is to prospectively collect procedural and follow-up data of all patients submitted to a clinically indicate LAAC in order to assess the impact of patient characteristics, procedural technique (imaging used to guide/plan procedure, device implanted, post-procedural drug regimens, etc.) on procedural safety and efficacy. The endpoints will be assessed by means of clinical follow-up at 1-3-5 years after LAAC and imaging exams (TEE at1-3 months, CCTA at 1-13months).

Conditions

• Atrial Fibrillation
• Cardiovascular Diseases
• Thromboembolism

Interventions

Type	Name	Description
OTHER	Use of echocardiography guidance for LAAC	Since August 2015, the echocardiography is routinely used by majority of operators to guide LAAC

Timeline

• Start date: 2015-08-12
• Primary completion: 2023-06-01
• Completion: 2027-06-01
• First posted: 2020-11-13
• Last updated: 2023-02-22

Locations

1 site across 1 country: Switzerland