NCT04625179

Melatonin and Hyaluronic Acid in Maxillary Sinus Augmentation

Evaluation of Melatonin and Hyaluronic Acid in Maxillary Sinus Augmentation (a Randomized Controlled Clinical Trial)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 16 (actual)
• Sponsor: Hams Hamed Abdelrahman · Academic / Other
• Sex: All
• Age: 30 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

melatonin proved an ability to repair bone defects and enhance osseointegration of dental implants. Also, hyaluronic acid has osteopromoting properties. the effect of melatonin and hyaluronic acid on the newly formed bone in maxillary sinus augmentation was evaluated

Detailed description

16 participants with missing maxillary posterior teeth and residual alveolar ridge of at least 5 mm will be equally and randomly divided into two groups. The study group will receive melatonin and hyaluronic acid after sinus membrane elevation and simultaneous implant placement while the control group will not receive any materials after sinus membrane elevation and simultaneous implant placement.

Conditions

• Edentulous; Alveolar Process, Atrophy

Interventions

Type	Name	Description
OTHER	Melatonin and hyaluronic acid and sinus membrane elevation	3 mg melatonin powder mixed with 0.2% hyaluronic acid gel will be placed to fill the sinus space and around the implant apex.
PROCEDURE	sinus membrane elevation without any materials	No materials will be placed at the sinus space.

Timeline

• Start date: 2019-12-03
• Primary completion: 2020-12-07
• Completion: 2020-12-07
• First posted: 2020-11-12
• Last updated: 2020-12-17

Locations

1 site across 1 country: Egypt