NCT04624386

Evaluating Oxidative Stress in Menopause

Evaluating Oxidative Stress in Postmenopausal Women

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 77 (actual)
• Sponsor: Sisli Hamidiye Etfal Training and Research Hospital · Academic / Other
• Sex: Female
• Age: 30 Years – 75 Years
• Healthy volunteers: Accepted

Summary

Thiol disulfide levels will be determined using venous blood samples from pre- and postmenopausal women to evaluate oxidative stress in menopause. Furthermore, oxidative stress will be assessed according to age, and years since the start of menopause. Also, whether the presence of menopause related osteoporosis has any association with oxidative stress will be determined.

Detailed description

A total of 77 subjects are divided into two groups: study group (postmenopausal women) and control group premenopausal women). Biometric data such as age, bmi, obstetric anamnesis, history of komorbidities, PAP smear results are recorded. Mammography results, dexa scores of post menopausal women are also obtained. Venous blood samples from all subjects are collected. Thiol disulfide levels will be determined from serum samples. Thiol disulfide levels will first be compared between the study and the control group in order to determine the oxidative stress in menopause. In secondary evaluation years of menopause, age, and dexa scores will be included.

Conditions

• Menopause
• Oxidative Stress

Interventions

Type	Name	Description
OTHER	Thiol disulfide level	Venous blood is collected from all subjects and thiol disulfide levels will be determined from the serum samples obtained from the venous blood.

Timeline

• Start date: 2020-08-30
• Primary completion: 2020-10-30
• Completion: 2020-11-04
• First posted: 2020-11-10
• Last updated: 2020-12-02

Locations

1 site across 1 country: Turkey (Türkiye)