NCT04624334

Non-invasive Assessment of Colonic Motility

Electro-Entero-Graphy (EEnG) for Non-invasive Diagnosis of Motility Disorders of the Bowel

• Status: Terminated
• Phase: —
• Study type: Observational
• Enrollment: 34 (actual)
• Sponsor: Radboud University Medical Center · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

The current diagnostic process of colonic motility disorders often takes a long time and involves multiple invasive, painful and/or unnecessary diagnostic procedures. To improve this diagnostic process, the potential of Electro-Entero-Graphy (EEnG) is investigated. During the EEnG procedure, several surface electrodes are positioned (under ultrasound guidance) on the abdomen so that electrical activity originating in the colon can be measured. Measurements will be performed after a period of fasting (when the colon is 'silent') and just after a meal (when the colon is moving) in both participants suffering from colonic motility disorders and healthy controls. It is hypothesized that these measurements are an indication of colonic motility and can be used as a diagnostic tool for colonic motility disorders. It is also hypothesized that this EEnG procedure is not more burdensome than the Gold Standard procedures for diagnosing colonic motility disorders. This will be assessed using questionnaires.

Conditions

• Colon Disease
• Functional Constipation
• Electroenterography
• Slow Transit
• Hirschsprung Disease

Interventions

Type	Name	Description
OTHER	Elektro-Entero-Graphy procedure	Fasting, after which pre- and postprandial EEnG measurements are performed.
OTHER	EEnG Questionnaire	Filling out questionnaire about EEnG procedure.
OTHER	Gold Standard Questionnaire	Filling out questionnaire about Gold Standard diagnostic used to diagnose colonic motility disorder.

Timeline

• Start date: 2021-02-25
• Primary completion: 2022-05-12
• Completion: 2022-05-12
• First posted: 2020-11-10
• Last updated: 2022-05-19

Locations

1 site across 1 country: Netherlands