NCT04623840

Combined Effect of Continuous and Interval in Addition to Tadalafil Drug on Erectile Dysfunction

Obesity-induced ED Response to Combined Effect of Tadalafil Drug in Addition to Interval and Continuous Training

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Cairo University · Academic / Other
• Sex: Male
• Age: 40 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

Erectile dysfunction (ED) is the persistent inability to attain and maintain a sufficient erection to permit satisfactory sexual performance. ED, a condition closely related to cardiovascular morbidity and mortality, is frequently associated with obesity. The importance of reducing cardiovascular risk factors remains fundamental to the overall vascular good health of the man, and that includes sexual vascular health. ED shares similar modifiable risks factors with coronary artery disease (CAD). Lifestyle modification that targets CAD risk factors may also lead to improvement in ED.

Detailed description

Sixty obese men with ED complaints will be divided to two groups, exercised and non-exercised groups; n= 30 patients in every group. Both groups will receive five milligrams of tadalafil one time per day for 8 weeks but the exercised group only will receive - in addition to tadalafil - combined continuous and interval aerobic training, 3 session weekly for 8 weeks after detecting their target heart rate via the cardiopulmonary exercise test.

Conditions

• Erectile Dysfunction

Interventions

Type	Name	Description
OTHER	Tadalafil 5Mg Tab + continuous and interval exercise	(n=30) will be sedentary obese men with ED. All participants will receive five milligrams of tadalafil, one time per day, in addition to 3 sessions, per week, of combined continuous and interval aerobic exercise for eight weeks
DRUG	Tadalafil 5Mg Tab	(n=30) will be sedentary obese men with ED. All participants will receive five milligrams of tadalafil, one time per day, for eight weeks

Timeline

• Start date: 2020-10-12
• Primary completion: 2021-02-28
• Completion: 2021-03-30
• First posted: 2020-11-10
• Last updated: 2020-11-10

Locations

1 site across 1 country: Egypt