NCT04619381

Causes of Health Disparities in African Americans With Coronary Artery Disease on Clopidogrel

Investigation of the Causes of Health Disparities in African Americans With Coronary Artery Disease on Clopidogrel

• Status: Withdrawn
• Phase: —
• Study type: Observational
• Enrollment: 0 (actual)
• Sponsor: Vanderbilt University Medical Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

African Americans with coronary artery disease who have been prescribed clopidogrel (also known as Plavix), an antiplatelet drug will be enrolled. The purpose of this study is to help identify why African Americans are at an increased risk of having a major heart attack or stroke after a common procedure to open up blocked arteries with stents. The knowledge to be gained from this study includes: 1. A better understanding of the metabolism of the antiplatelet drug, clopidogrel, and abnormal platelet function in African Americans; this understanding may provide a basis for potential future therapy 2. A better understanding of challenges to taking clopidogrel as prescribed by a doctor and opinions about a genetic test related to this medicine.

Conditions

• Coronary Artery Disease

Interventions

Type	Name	Description
BEHAVIORAL	CORONARY ARTERY DISEASE AND CLOPIDOGREL: PATIENT SURVEY	Survey is a non-standardized assessment of demographics, medication compliance and reasons for non- compliance.

Timeline

• Start date: 2021-03-19
• Primary completion: 2021-03-19
• Completion: 2021-03-19
• First posted: 2020-11-06
• Last updated: 2021-04-01

Locations

1 site across 1 country: United States