Trials / Unknown
UnknownNCT04618887
A Comparative Study of GPI's DBS and Pallidotomy in the Treatment of Meige Syndrome
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 100 (estimated)
- Sponsor
- Peking University People's Hospital · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Not accepted
Summary
In this study, we will compare the degree of postoperative symptom improvement, postoperative complication rate, postoperative quality of life improvement degree of patients with Meige syndrome undergoing pallidotomy (unilateral globus palliotomy) and deep brain stimulation (unilateral globus pallidus) ,in order to get the conclusion of the comparison of the clinical efficacy of the two surgical plans. In addition, possible predictive factors such as age, gender, age of onset, length of disease course, scale baseline score, preoperative brain PET-CT function analysis and other possible predictive factors are added for analysis, in order to find predictive factors that can guide the choice of surgical options.
Conditions
- Meige Syndrome
- Meigs Syndrome
- Meige Disease
- Meig Syndrome
- Blepharospasm
- Blepharospasm of Left Eyelid
- Blepharospasm of Right Eyelid
- Blepharospasm of Both Eyelids
- Blepharospasm Oromandibular Dystonia
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | pallidotomy | deep brain nuclei lesion of GPi |
| PROCEDURE | deep brain stimulation | deep brain stimulation of GPi |
Timeline
- Start date
- 2020-01-01
- Primary completion
- 2022-11-01
- Completion
- 2023-12-01
- First posted
- 2020-11-06
- Last updated
- 2020-11-06
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT04618887. Inclusion in this directory is not an endorsement.