NCT04614129

Lung Cancer Risk and Early Detection in Firefighters

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 734 (actual)
• Sponsor: Massachusetts General Hospital · Academic / Other
• Sex: All
• Age: 40 Years – 80 Years
• Healthy volunteers: Accepted

Summary

This study will evaluate whether LDCT findings differ between firefighters and non-fighters, the relationship between occupational exposures and LDCT findings, and whether a proteomics assay can further risk-stratify screen-detected nodules among a study population of 850 current and retired firefighters and 1,120 matched controls.

Conditions

• Lung Cancer
• Lung Diseases

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Low Dose CT	All participants will have a low dose chest CT either within one year of enrollment or after enrollment

Timeline

• Start date: 2021-03-02
• Primary completion: 2025-11-01
• Completion: 2025-11-01
• First posted: 2020-11-03
• Last updated: 2025-11-24

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study