NCT04612140

STereotactic Ablative Radiosurgery of Recurrent Ventricular Tachycardia in Structural Heart Disease

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 22 (actual)
• Sponsor: University Hospital Ostrava · Academic / Other
• Sex: All
• Age: 20 Years
• Healthy volunteers: Not accepted

Summary

A multicentre trial on clinical effects of radiosurgical ablation of ventricular tachycardia (VT).

Detailed description

Patients with previously failed conventional RF catheter ablation will be randomized to radiosurgery (active treatment group) or repeated catheter ablation (control treatment group). Details on inclusion and exclusion criteria are provided below. Randomization Eligible patients will be assigned to 2 treatment arms - radiosurgery (active arm) or repeated catheter ablation (control arm) in 1:1 fashion by covariate-adaptive randomization algorithm considering age, gender, etiology of structural heart disease (SHD), left ventricular (LV) ejection fraction, and serum B-type natriuretic peptide (NT-proBNP) level.

Conditions

• Ventricular Tachycardia

Interventions

Type	Name	Description
PROCEDURE	Radiosurgery	The study subjects randomized in this study arm will undergo a radiosurgery procedure.
PROCEDURE	Repeated catheter ablation	The study subjects randomized in this study arm will undergo repeated catheter ablation.

Timeline

• Start date: 2020-10-01
• Primary completion: 2024-06-30
• Completion: 2024-06-30
• First posted: 2020-11-02
• Last updated: 2025-06-04

Locations

2 sites across 1 country: Czechia